Achievements

論 文


国内学会発表一覧      国際学会発表一覧       受賞一覧 


2019年
55) Koji Fukui, Neuroprotective and anti-obesity effects of tocotrienols; Recommended whole rice intake, Journal of Nutritional Science and Vitaminology, in press

54) Koji Fukui*, Masashi Shirai, Takeyuki Ninuma, Yugo Kato, Antiobesity effects of tocotrienols and bran in high-fat diet-treated mice, Nutrients, 11(4), 830, 2019, (*Corresponding Author), PubMed, MDPI (Full Text)

53) Shuhei Nakamura, Masaki Oba, Mari Suzuki, Atsushi Takahashi, Tadashi Yamamuro, Mari Fujiwara, Kensuke Ikenaka, Satoshi Minami, Namie Tabata, Kenichi Yamamoto, Sayaka Kubo, Ayaka Tokumura, Kanako Akamatsu, Yumi Miyazaki, Tsuyoshi Kawabata, Maho Hamasaki, Koji Fukui, Kazunori Sango, Yoshihisa Watanabe, Yoshitsugu Takabatake, Tomoya Kitajima, Yukinori Okada, Hideki Mochizuki, Yoshitaka Isaka, Adam Antebi, and Tamotsu Yoshimori, Suppression of autophagic activity by Rubicon is a signature of aging, Nature Communications, 10(1), 847, 2019, PubMed, Nature.com (Full Text)

52) Akihiko Hatano, Yuichi Kanno, Yuya Kondo, Yuta Sunaga, Hatsumi Umezawa, Koji Fukui, Use of a deoxynojirimycin-fluorophore conjugate as a cell-specific imaging probe targeting alpha-glucosidase on cell membranes, Bioorganic & Medicinal Chemistry, 27, 859-864, 2019, PubMed, Science direct (Full Text)

51) Koji Fukui*, Shunsuke Okihiro, Yuuka Ohfuchi, Minae Hashimoto, Yugo Kato, Naoki Yoshida, Kaho Mochizuki, Hiroki Tsumoto, Yuri Miura, Proteomic study on neurite responses to oxidative stress: Search for differentially expressed proteins in isolated neurites of N1E-115 cells, Journal of Clinical Biochemistry and Nutrition, 64(1), 36-44, 2019 (*Corresponding Author), PubMed, J-Stage (Full Text)


2018年
50) 大場柾樹,永井義隆,福井浩二,三五一憲,鈴木マリ,オートファジー抑制蛋白質Rubiconの発現抑制はポリグルタミン病モデルショウジョウバエの神経症状を改善させる,日本病態生理学会誌,27(3), p28-32, 2019

49) Koji Fukui, Neuroprotective effect of tocotrienols, Proceeding of the 12th South East Acean Technical University Consortium Symposium (SEATUC2018), Mar. 12-13, Gadjah Mada, Indonesia, 2018 (*Proceedings with peer review, Corresponding Author)

48) Yugo Kato, Koji Fukui, The effect of tocotrienols on long-term high-fat diet-treated mice, Proceeding of the 12th South East Acean Technical University Consortium Symposium (SEATUC2018), Mar. 12-13, Gadjah Mada, Indonesia, 2018 (*Proceedings with peer review, Corresponding Author)


2017年
47) Shunsuke Okihiro, Yuka Ofuchi, Hiroki Tsumoto, Yuri Miura, Koji Fukui, Determination of neurite degeneration method and identification of neurite specific proteins in hydrogen peroxide-treated N1E-115 cells, Proceeding of the 11th South East Asean Technical University Consortium Symposium (SEATUC2017), p1-5, 2017 (*Proceedings with peer review, Corresponding Author)

46) Masashi Shirai, Koji Fukui, The effect of tocotrienols on high-fat diet-treated mice. Proceeding of the 11th South East Asean Technical University Consortium Symposium (SEATUC2017), p1-5, 2017 (*Proceedings with peer review, Corresponding Author)

45) Akihiko Hatano, Yuichi Kanno, Yuta Kondo, Yuka Sunaga, Hatsumi Umezawa, Munehiro Okada, Hideshi Yamada, Ren Iwaki, Atsushi Kato and Koji Fukui, Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for alpha-glucosidase recognition, Bioorganic & Medical Chemistry, 25(2), 773-778, 2017, PubMed, SicenceDirect (Full Text)

2016年
44) 福井浩二、中村啓佑、白井将志、青木由典、小池泰介、浦野四郎、コレステロール投与マウスでの認識機能障害の誘因とビタミンEによる防御、ビタミンE研究の進歩、17、30-36、2016 (Corresponding Author)

43) Saki Nakamura, Ayumi Nakanishi, Shunsuke Okihiro, Shiro Urano, Koji Fukui, Ionomycin-induced calcium influx induces neurite degeneration in mouse neuroblastoma cells: Analysis of a time-lapse live cell imaging system, Free Radical Research, 50(11), 1214-1225, 2016. Pub Med, Taylor & Francis Online (Full text, Open Access), (Corresponding Author)

42) 福井浩二、酸化ストレスによる神経突起変性の誘因、ストレスと老化・疾患、基礎老化研究、40(3)、17-21, 2016 (Invited)

41) David Tweedie, Koji Fukui, Yazhou Li, Qian-sheng Yu, Shani Barak, Ian A Tamargo, Vardit Rubovitch, Harold W Holloway, Elin Lehrmann, William H Wood III, Yongqing Zhang, Kevin G Becker, Evelyn Perez, Henriette Van Praag, Barry J Hoffer, Robert E Becker, Chaim G Pick, Nigel H Greig, Cognitive impairments induced by concussive mild traumatic brain injury in mouse are ameliorated by treatment with phenserine via mulyiple non-cholinergic mechanisms, PLos One, 2016 Jun 2;11(6):e0156493. doi: 10.1371/journal.pone.0156493. Pub Med, PLOS ONE (Full text) (Double first author)

40) Koji Fukui, Reactive oxygen species induce neurite degeneration before induction of cell death, Journal of Clinical Biochemistry and Nutrition, 59(3), 155-159, 2016 Pub Med, J-Stage (Full Text)

39) Joanne Allard, Evelyn J Perez, Koji Fukui, Priscilla Carpenter, Donald K Ingram, Rafael de Cabo, Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice, Behavioral Brain Research, 301, 1-9, 2016, Pub Med

38) Nozomi Kaneai, Kasumi Sumitani, Koji Fukui, Taisuke Koike, Hirokatsu Takatsu, Shiro Urano, Tocotrienols improve learning and memory deficit of aged-rats, Journal of Clinical Biochemistry and Nutrition, 58(2), 114-121, 2016, J-Stage (Full Text)


2015年
37) Koji Fukui, Keisuke Nakamura, Masashi Shirai, Hirokatsu Takatsu, Shiro Urano, Long-term vitamin E-deficient mice exhibit cognitive dysfunction via elevation of brain oxidation, Journal of Nutritional Science and Vitaminology, 61(5), 362-368, 2015, Pub Med, J-Stage(Full Text) (Corresponding Author)

2014年
36) Koji Fukui, Asato Masuda, Aya Hosono, Ryoma Suwabe, Kenya Yamashita, Tadashi Shinkai, Shiro Urano, Changes in microtubule-related proteins and autophagy in long-term vitamin E deficient mice, Free Radical Research, 48(6), 649-658, 2014, Pub Med, Taylor & Francis Online (Full text, Open access). (Corresponding Author)

35) 福井浩二、トコトリエノールによる神経保護作用の可能性に関する研究、ビタミン、88(1)、11-17、2014

2013年
34) Koji Fukui, Hidekazu Sekiguchi, Hirokatsu Takatsu, Taisuke Koike, Tatsuro Koike, Shiro Urano, Tocotrienol prevents AAPH-induced neurite degeneration in neuro2a cells, Redox Report, 18(6), 238-244, 2013, Pub Med, Maney Publishing (Corresponding Author)

33) Nozomi Kaneai, Koji Fukui, Taisuke Koike, Shiro Urano, Vitamin E prevents hyperoxida-induced loss of soluble N-etylmaleimide-sensitive fusion protein attachment protein receptor proteins in the rat neuronal cytoplasm, Biological and Pharmaceutical Bulltin, 36(9), 1500-1502, 2013, Pub Med, J-Stage(Full Text)


2012年
32) Nozomi Kaneai, Koji Fukui, Taisuke Koike, Shiro Urano, Changes in the levels of CAM kinase U and synapsin T caused by oxidative stress in the rat brain, and its prevention by vitamin E, Advances in Bioscience and Biotechnology, 3(8), 1199-1205, 2012, Scientific Research (Open Access)

31) 金相 希、新井正也、高津博勝、福井浩二、浦野四郎、神経末端タンパク質への酸化ストレスの影響およびビタミンEの効果、ビタミンE研究の進歩、15、26-33、2012

30) 牛木啓友、本條達樹、川上浩彬、高津博勝、新海 正、浦野四郎、福井浩二、酸化ストレスによる神経細胞の変化とビタミンEによる保護効果について、ビタミンE研究の進歩、15、34-39、2012 (Corresponding Author)

29) Koji Fukui, Hiroaki Kawakami, Tatsuki Honjo, Reiko Ogasawara, Hirokatsu Takatsu, Tadashi Shinkai, Tatsuro Koike, Shiro Urano, Vitamin E deficiency induces axonal degeneration in mouse hippocampal neurons, Journal of Nutritional Science and Vitaminology, 58(6), 377-383, 2012, Pub Med, J-Stage (Full Text) (Corresponding Author)

28) Koji Fukui, Keisuke Ushiki, Hirokatsu Takatsu, Tatsuro Koike, Shiro Urano, Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells, Free Radical Research, 46(2), 184-193, 2012, Taylor & Francis Online (Full text, Open access), Pub Med. (Corresponding Author)

27) Nozomi Kaneai, Masaya Arai, Hirokatsu Takatsu, Koji Fukui, Shiro Urano, Vitamin E inhibits oxidative stress-induced denaturation of nerve terminal proteins involved in neurotransmission, Journal of Alzheimer's Disease, 28(1), 183-189, 2012, IOS Press, Pub Med,

2011年
26) 福井浩二、高津博勝、浦野四郎、過酸化水素投与による神経突起傷害とビタミンEによる神経保護効果についての研究、ビタミン、85(10), 531-537、2011 (Corresponding Author)

25) Koji Fukui, Hirokatsu Takatsu, Tasuro Koike, Shiro Urano, Hydrogen peroxide induces neurite degeneration: Prevention by tocotrienols, Free Radical Research, 45(6), 681-691, 2011, Pub Med, Taylor & Francis Online (Full text, open access) (Corresponding Author).

24) Masaya Arai, Mitsunari Saito, Hirokatsu Takatsu, Koji Fukui, Shiro Urano, Dysfunction of the fusion of pre-synaptic plasma membranes and synaptic vesicles caused by oxidative stress, and its prevention by vitamin E, Journal of Alzheimer's Disease, 24(4), 759-766, 2011, Pub Med, IOS Press.

2010年
23) 福井浩二、高津博勝、浦野四郎、酸化的ストレスによる神経突起傷害とビタミンEによる保護効果について、ビタミンE研究の進歩、14、33-38、2010

2009年
22) Hitokatsu Takatsu, Masahiro Ogata, Koji Fukui, Tadahiro Takeda, Toyoshige Endo, Shiro Urano, Inhibitory effects of Lysichiton camtschatcense extracts on Fe2+/ascorbate-induced lipid peroxidation in rat kidney and brain homogenates, Journal of Natural Medicines, 63(3), 364-367, 2009, Pub Med, Springer Link

21) Koji Fukui, Shiro Urano, Tatsuro Koike, Releasing factors from mature neurons modulate microglial survival via purinergic receptor activation, Neuroscience Letters, 456(2), 64-68, 2009, Pub Med
(Corresponding Author)

2008年
20) Koji Fukui, Kouichi Abe, Shiro Urano, Vitamin E improve cognitive deficit of rats caused by oxidative stress and aging, Journal of Clinical Biochemistry and Nutriton, 43, Suppl, 1, 47-50, 2008,

19) Kei Ohwada, Hironobu Takeda, Makiko Yamazaki, Hiroshi Isogai, Masahiko Nakano, Masao Shimomura, Koji Fukui and Shiro Urano, Pyrroloquinoline quinone (PQQ) Prevents Cognitive Deficit Caused by Oxidative Stress in Rats, Journal of Clinical Biochemistry and Nutriton, 42(1), 29-34, 2008 Pub Med, J-stage (Full Text)

2007年
18) Ekatherina Touma, Satoko Kato, Koji Fukui, Tatsuro Koike, Calpaine-mediated cleavage of collapsing response mediator protein-2 (CRMP-2) during neurite degeneration, European Journal of Neuroscience, 26(12, 3368-3381, 2007, Pub Med), Science DIrect

17) Yi Yang, Koji Fukui, Tatsuro Koike and Xiaoxiang Zheng, Induction of Autophagy in Neurite Degeneration of Mouse Superior Cervical Ganglion Neurons, European Journal of Neuroscience, 26(10), 2979-2988, 2007, Pub Med,,Science Direct

16) Yi Yang, Taku Kawataki, Koji Fukui, and Tatsuro Koike, Cellular Zn2+ Chelators Cause Dying-Back Neurite Degeneration Associated with Energy Impairment, Journal of Neuroscience Research, 85(13), 2844-2855, 2007, Pub Med

15) Hajime Mori, Masayuki Oikawa, Tsuyoshi Tamagami, Hisokazu Kumaki, Reiko Nakaune, Jun Amano, Yukinori Akinaga, Koji Fukui, Kouichi Abe and Shiro Urano, Oxidized proteins in astrocytes generated in a hyperbaric atmosphere induce neuronal apoptisis, Journal of Alzheimer's Disease, 11(2), 165-174, 2007, Pub Med


2006年
14) Koji Fukui, Valentina V. Ostapenko, Kouichi Abe, Takahiro Nishide, Motoshige Miyano, Masatoshi Mune, Susumu Yukawa and Iwao Nishide, Changes in Plasma Alpha and Gamma Tocopherol Levels before and after Long-Term Local Hyperthermia in Cancer Patients, Free Radical Research, 40(8), 893-899, 2006, Pub Med, Taylor & Francis Online, (Corresponding Author)

13) Mikako Goda, Tsunahiko Hirano, Koji Fukui, Toshiyuki Yamagata, Yuko Yamagata, Masanori Nakanishi, Kazuhito Ueshima, Kazuto Matsunaga, Yoshiaki Minakata and Masakazu Ichinose, New effects of theophylline in patients with chronic obstructive pulmonary disease: Anti-inflammatory action and its underlying mechanism, Journal of Wakayama Medical Society, 57(1), 8-13, 2006,

12) Naoomi Omoi, Masaya Arai, Mitsunari Saito, Hirokatsu Takatsu, Akira Shibata, Kenji Fukuzawa, Kazue Sato, Kouichi Abe, Koji Fukui and Shiro Urano, Influence of oxidative stress on fusion of pre-synaptic plasma membranes of the rats brain with phosphatidyl choline liposome, and protective effect of vitamin E, Journal of Neutritional Science and Vitaminology, 52(4), 248-255, 2006, Pub Med, J-Stage (Full Text)

11) Tomoko Nishio, Ryota Miyadera, Ryuta Sakai, Kouichi Abe, Hideo Kanazawa, Koji Fukui and Shiro Urano, Increased F2-isoprpstane levels in the rat brain and plasma caused by oxidative stress and aging and inhibitory effect of vitamin E, Journal of Clinical Biochemistry and Neutriton, 38(3), 161-166, 2006, J-Stage (Full Text)

2005年
10) Koji Fukui, Hisokatsu Takatsu, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe and Shiro Urano, Appearance of β-amyloid-like substances and delayed-type apoptosis in rat hippocampus CA1 region through aging and oxidative stress, Journal of Alzheimer's Disease, 8(3), 299-309, 2005, Pub Med

9) Hiroto tanaka, Motoshige Miyano, Hiroki Ueda, Koji Fukui, Masakazu Ichinose, Changes in serum and red blood cell membrane lipids in patients treated with interferon ribavirin for chronic hepatitis C, Clinical Experimental Medicine, 5(4), 190-195, 2005, Pub Med

8) 福井浩二、宗 正敏、宮野元成、バレンチナ オスタペンコ、西出孝啓、湯川 進む、西出 巌、温熱療法とビタミンE量の変動、ビタミンE研究の進歩、11、140-143、2005 (Corresponding Author)

7) 福井浩二、宗 正敏、斉藤三也、新井秀和、高橋武幸、新海 正、鈴木捷三、阿部皓一、浦野四郎、酸化的ストレスで発現する海馬領錐体細胞アポトーシス、βアミロイド様物質発現、認識機能不全、そしてビタミンEの阻害効果、ビタミンE研究の進歩、11、178-182、2005

2003年
6) Koji Onodera, Naoomi Omoi, Koji Fukui, Takahiro Hayasaka, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe, Shiro Urano, Oxidative damage of rat cerebral cortex and hippocampus and changes in antioxidative defense systems caused by hyperoxia, Free Radical Research, 37(4), 367-372, 2003, Pub Med, Taylor & Francis Online

5) Koji Fukui, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe, Shiro Urano, Cognitive dysfunction cauzed by oxidative stress and aging, Biomedical Gerontology, 27, 41-44, 2003

4) Koji Fukui, Tadashi Shinkai, Kouichi Abe and Shiro Urano, Inhibitory Effect of Vitamin E on Cognitive Impairment of Rats Caused by Oxidative Stress and Aging, Proceeding of 2nd China-Japan International Conference on Vitamins, China Medicine Association and The Vitamin Society of Japan, 317-320, 2003

2002年
3) 福井浩二、斉藤三也、新海 正、 鈴木捷三、阿部皓一、浦野四郎、ラット海馬領の酸化的ストレスによる遅延型アポトーシスの発生とビタミンE欠乏の影響、ビタミンE研究の進歩、10、150-153、2002

2) Koji Fukui, naoomi Omoi, Takahiro Hayasaka, Tadashi Shinkai, Shozo Suzuki, Kouichi Abe, Shiro Urano, Cognitive impairment of rats caused by oxidative stress and aging, and its prevention by vitamin E, Annal of the New York Academy of Sciences, 959, 275-284, 2002, Pub Med


2001年
1) Koji Fukui, Koji Onodera, Tadashi Shinkai, Shozo Suzuki, Shiro Urano, Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems, Annal of the New York Academy of Sciences, 928, 169-176, 2001, Pub Med
芝浦工業大学
システム理工学部 生命科学科 分子細胞生物学研究室